Dr. Jonathan Wren, director of the Bioinformatics and Pathways Core associated with OMRF’s Developmental Biology COBRE, provides consultation and support for this COBRE. He helps with statistical issues such as power analysis and choosing the most appropriate statistical test given the experimental design.
Dr. Wren also has several state-of-the-art software resources for analysis of high-throughput data such as microarrays and proteomics, and software resources helpful to this Core, which include:
- IRIDESCENT for literature-based relationship network analysis between genes, diseases, chemicals, phenotypes and tissues
- GAMMA (Global Microarray Meta-Analysis) for predicting gene function based upon transcriptional network correlations
- GenomeRunner for analysis of genomic commonalities